RFTN1 Antibody
Product Sizes
100ul
£359.00
OACD06891-100UL
1ml
£1016.00
OACD06891-1ML
About this Product
- SKU:
- OACD06891
- Additional Names:
- cell migration-inducing gene 2 protein;MIG2;PIB10;PIG9;proliferation-inducing protein 10;proliferation-inducing protein 9;raftlin;raft-linking protein.
- Clonality:
- Polyclonal
- Concentration:
- 0.5 mg/ml
- Extra Details:
- Involved in protein trafficking via association with clathrin and AP2 complex (PubMed:27022195; PubMed:21266579). Upon bacterial lipopolysaccharide stimulation; mediates internalization of TLR4 to endosomes in dendritic cells and macrophages; and internalization of poly(I:C) to TLR3-positive endosomes in myeloid dendritic cells and epithelial cells; resulting in activation of TICAM1-mediated signaling and subsequent IFNB1 production (PubMed:27022195; PubMed:21266579). Involved in T-cell antigen receptor-mediated signaling by regulating tyrosine kinase LCK localization; T-cell dependent antibody production and cytokine secretion (By similarity). May regulate B-cell antigen receptor-mediated signaling (PubMed:12805216). May play a pivotal role in the formation and/or maintenance of lipid rafts (PubMed:12805216).
- Gene Details:
- raftlin; lipid raft linker 1
- Host:
- Rabbit
- Immunogen:
- Range: Ser288 - Leu520
- Isotype:
- IgG
- Molecular Weight:
- 63 kDa
- Protein Details:
- Raftlin
- Purification:
- Affinity Purified; Protein A Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2Â[o]C to 8Â[o]C|-20Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
