PTPRJ Antibody
Product Sizes
100ul
£326.00
OACD06836-100UL
1ml
£912.00
OACD06836-1ML
About this Product
- SKU:
- OACD06836
- Additional Names:
- AI450271;BET;By;Byp;CD148;colon tumor susceptibility 1;DEP-;DEP-1;HPTP beta-like tyrosine phosphatase;protein-tyrosine phosphatase eta;Protein-tyrosine phosphatase receptor type J;Ptpb2;PTPbeta2;receptor-type tyrosine-protein phosphatase eta;RP;R-PTP-eta;RPTPJ;R-PTP-J;Scc;Scc-;Scc1;Scc-1;susceptibility to colon cancer 1.
- Clonality:
- Polyclonal
- Concentration:
- 0.5 mg/ml
- Extra Details:
- Tyrosine phosphatase which dephosphorylates or contributes to the dephosphorylation of CTNND1; FLT3; PDGFRB; MET; RET; KDR; LYN; SRC; MAPK1; MAPK3; EGFR; TJP1; OCLN; PIK3R1 and PIK3R2. Plays a role in cell adhesion; migration; proliferation and differentiation. Involved in vascular development. May be involved in the mechanism of contact inhibition of cell growth. Regulator of macrophage adhesion and spreading. Positively affects cell-matrix adhesion. Positive regulator of platelet activation and thrombosis. Negative regulator of cell proliferation. Negative regulator of PDGF-stimulated cell migration; through dephosphorylation of PDGFR. Positive regulator of endothelial cell survival; as well as of VEGF-induced SRC and AKT activation; through KDR dephosphorylation. Negative regulator of EGFR signaling pathway; through EGFR dephosphorylation. Enhances the barrier function of epithelial junctions during reassembly. Negatively regulates T-cell receptor (TCR) signaling. Upon T-cell TCR activation; it is up-regulated and excluded from the immunological synapses; while upon T-cell-antigen presenting cells (APC) disengagement; it is no longer excluded and can dephosphorylate PLCG1 and LAT to down-regulate prolongation of signaling.
- Gene Details:
- protein tyrosine phosphatase; receptor type; J
- Host:
- Rabbit
- Immunogen:
- Range: Thr567 - Asn842
- Isotype:
- IgG
- Molecular Weight:
- 137 kDa
- Protein Details:
- Receptor-type tyrosine-protein phosphatase eta
- Purification:
- Affinity Purified; Protein A Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2Â[o]C to 8Â[o]C|-20Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
