PTF1A Antibody
Product Sizes
100ul
£333.00
OACD06786-100UL
1ml
£933.00
OACD06786-1ML
About this Product
- SKU:
- OACD06786
- Additional Names:
- bHLH transcription factor p48;bHLHa29;class A basic helix-loop-helix protein 29;class II bHLH protein PTF1A;exocrine pancreas-specific transcription factor p48;p48;p48 DNA-binding subunit of transcription factor PTF1;PACA;PAGEN2;pancreas specific transcription factor; 1a;pancreas transcription factor 1 subunit alpha;Pancreas-specific transcription factor 1a;PTF1-p48.
- Clonality:
- Polyclonal
- Concentration:
- 0.82 mg/ml
- Extra Details:
- Transcription factor implicated in the cell fate determination in various organs. Binds to the E-box consensus sequence 5'-CANNTG-3'. Plays a role in early and late pancreas development and differentiation. Important for determining whether cells allocated to the pancreatic buds continue towards pancreatic organogenesis or revert back to duodenal fates. May be involved in the maintenance of exocrine pancreas-specific gene expression including ELA1 and amylase. Required for the formation of pancreatic acinar and ductal cells. Plays an important role in cerebellar development. Directly regulated by FOXN4 and RORC during retinal development; FOXN4-PTF1A pathway plays a central role in directing the differentiation of retinal progenitors towards horizontal and amacrine fates.
- Gene Details:
- pancreas associated transcription factor 1a
- Host:
- Rabbit
- Immunogen:
- Range: Gln177 - Ser328
- Isotype:
- IgG
- Molecular Weight:
- 35 kDa
- Protein Details:
- Pancreas transcription factor 1 subunit alpha
- Purification:
- Affinity Purified; Protein A Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2Â[o]C to 8Â[o]C|-20Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
