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Antibodies

PSMD10 Antibody

Product Sizes
100ul
£359.00
OACD06769-100UL
1ml
£1020.00
OACD06769-1ML
About this Product
SKU:
OACD06769
Additional Names:
26S proteasome non-ATPase regulatory subunit 10;26S proteasome regulatory subunit p28;ankyrin repeat protein;dJ889N15.2;gankyrin;hepatocellular carcinoma-associated protein p28-II;p28;p28(GANK);proteasome (prosome; macropain) 26S subunit; non-ATPase; 10.
Clonality:
Polyclonal
Concentration:
0.5 mg/ml
Extra Details:
Acts as a chaperone during the assembly of the 26S proteasome; specifically of the PA700/19S regulatory complex (RC). In the initial step of the base subcomplex assembly is part of an intermediate PSMD10:PSMC4:PSMC5:PAAF1 module which probably assembles with a PSMD5:PSMC2:PSMC1:PSMD2 module. Independently of the proteasome; regulates EGF-induced AKT activation through inhibition of the RHOA/ROCK/PTEN pathway; leading to prolonged AKT activation. Plays an important role in RAS-induced tumorigenesis.
Gene Details:
proteasome 26S subunit; non-ATPase 10
Host:
Rabbit
Immunogen:
Range: Met1 - Gly226
Isotype:
IgG
Molecular Weight:
16 kDa
Protein Details:
26S proteasome non-ATPase regulatory subunit 10
Purification:
Affinity Purified; Protein A Purified
Shipping Conditions:
Blue Ice
Storage Conditions:
2Â[o]C to 8Â[o]C|-20Â[o]C
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody