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Antibodies

CD274 Antibody

Product Sizes
100ul
£316.00
OACD06351-100UL
1ml
£868.00
OACD06351-1ML
About this Product
SKU:
OACD06351
Additional Names:
A530045L16Rik;B7 homolog 1;B7h1;PD-;PDCD1 ligand 1;Pdcd1l;Pdcd1l1;Pdcd1lg1;Pdl1;programmed cell death 1 ligand 1.
Clonality:
Polyclonal
Concentration:
0.5 mg/ml
Extra Details:
Plays a critical role in induction and maintenance of immune tolerance to self. As a ligand for the inhibitory receptor PDCD1; modulates the activation threshold of T-cells and limits T-cell effector response (PubMed:11238124). The PDCD1-mediated inhibitory pathway is exploited by tumors to attenuate anti-tumor immunity and facilitate tumor survival (By similarity). May costimulate helper T-cell subsets through a yet unknown activating receptor (PubMed:11015443; PubMed:12719480).
Gene Details:
CD274 antigen
Host:
Rabbit
Immunogen:
Recombinant PDL (Leu48 - Thr290) expressed in E.coli
Isotype:
IgG
Protein Details:
Programmed cell death 1 ligand 1
Purification:
Affinity Purified; Protein A Purified
Shipping Conditions:
Blue Ice
Storage Conditions:
2Â[o]C to 8Â[o]C|-20Â[o]C
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody