NME1 Antibody
Product Sizes
100ul
£344.00
OACD05995-100UL
1ml
£955.00
OACD05995-1ML
About this Product
- SKU:
- OACD05995
- Additional Names:
- AL024257;expressed in non-metastatic cells 1; protein;metastasis inhibition factor NM23;NDK A;NDP;NDP kinase A;NDPK-A;NM23A;NM23-M;NM23-M1;non-metastatic cells 1; protein (NM23A) expressed in;nucleoside diphosphate kinase A;nucleoside-diphosphate kinase 1;nucleotide diphosphate kinase;tumor metastatic process-associated protein.
- Clonality:
- Polyclonal
- Concentration:
- 0.5 mg/ml
- Extra Details:
- Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism; using a phosphorylated active-site intermediate. Possesses nucleoside-diphosphate kinase; serine/threonine-specific protein kinase; geranyl and farnesyl pyrophosphate kinase; histidine protein kinase and 3'-5' exonuclease activities. Involved in cell proliferation; differentiation and development; signal transduction; G protein-coupled receptor endocytosis; and gene expression. Required for neural development including neural patterning and cell fate determination. During GZMA-mediated cell death; works in concert with TREX1. NME1 nicks one strand of DNA and TREX1 removes bases from the free 3' end to enhance DNA damage and prevent DNA end reannealing and rapid repair (By similarity).
- Gene Details:
- NME/NM23 nucleoside diphosphate kinase 1
- Host:
- Rabbit
- Immunogen:
- Range: Arg6 - Gln147
- Isotype:
- IgG
- Molecular Weight:
- 17 kDa
- Protein Details:
- Nucleoside diphosphate kinase A
- Purification:
- Affinity Purified; Protein A Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2Â[o]C to 8Â[o]C|-20Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
