NEIL3 Antibody
Product Sizes
100ul
£366.00
OACD05928-100UL
1ml
£1042.00
OACD05928-1ML
About this Product
- SKU:
- OACD05928
- Additional Names:
- AI449477;BC034753;C85903;DNA glycosylase FPG2;DNA glycosylase/AP lyase Neil3;endonuclease 8-like 3;endonuclease VIII-like 3;nei endonuclease VIII-like 3;nei-like protein 3.
- Clonality:
- Polyclonal
- Concentration:
- 0.5 mg/ml
- Extra Details:
- DNA glycosylase which prefers single-stranded DNA (ssDNA); or partially ssDNA structures such as bubble and fork structures; to double-stranded DNA (dsDNA). In vitro; displays strong glycosylase activity towards the hydantoin lesions spiroiminodihydantoin (Sp) and guanidinohydantoin (Gh) in both ssDNA and dsDNA; also recognizes FapyA; FapyG; 5-OHU; 5-OHC; 5-OHMH; Tg and 8-oxoA lesions in ssDNA. No activity on 8-oxoG detected. Also shows weak DNA-(apurinic or apyrimidinic site) lyase activity. In vivo; appears to be the primary enzyme involved in removing Sp and Gh from ssDNA in neonatal tissues. Seems to be an important facilitator of cell proliferation in certain populations; for example neural stem/progenitor cells and tumor cells; suggesting a role in replication-associated DNA repair.
- Gene Details:
- nei like 3 (E. coli)
- Host:
- Rabbit
- Immunogen:
- Range: Val2 - Val187
- Isotype:
- IgG
- Molecular Weight:
- 23 kDa
- Protein Details:
- Endonuclease 8-like 3
- Purification:
- Affinity Purified; Protein A Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2Â[o]C to 8Â[o]C|-20Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
