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Antibodies

MASP1 Antibody

Product Sizes
100ul
£326.00
OACD05451-100UL
1ml
£912.00
OACD05451-1ML
About this Product
SKU:
OACD05451
Additional Names:
AW048060;CCPII;complement factor MASP-3;complement-activating component of Ra-reactive factor;Cr;Crarf;mannan-binding lectin serine protease 1;mannose-binding lectin-associated serine protease 1;mannose-binding protein-associated serine protease;MASP-1;Masp1/3;ra-reactive factor serine protease p100;raRF;serine protease 5.
Clonality:
Polyclonal
Concentration:
0.5 mg/ml
Extra Details:
Functions in the lectin pathway of complement; which performs a key role in innate immunity by recognizing pathogens through patterns of sugar moieties and neutralizing them. The lectin pathway is triggered upon binding of mannan-binding lectin (MBL) and ficolins to sugar moieties which leads to activation of the associated proteases MASP1 and MASP2. Functions as an endopeptidase and may activate MASP2 or C2 or directly activate C3 the key component of complement reaction. Isoform 2 may have an inhibitory effect on the activation of the lectin pathway of complement or may cleave IGFBP5. Also plays a role in development.
Gene Details:
mannan-binding lectin serine peptidase 1
Host:
Rabbit
Immunogen:
Range: His25 - Arg453
Isotype:
IgG
Molecular Weight:
80 kDa
Protein Details:
Mannan-binding lectin serine protease 1
Purification:
Affinity Purified; Protein A Purified
Shipping Conditions:
Blue Ice
Storage Conditions:
2Â[o]C to 8Â[o]C|-20Â[o]C
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody