MAPRE1 Antibody
Product Sizes
100ul
£333.00
OACD05446-100UL
1ml
£933.00
OACD05446-1ML
About this Product
- SKU:
- OACD05446
- Additional Names:
- adenomatous polyposis coli-binding protein EB1;APC-binding protein EB1;EB1;end-binding protein 1;microtubule-associated protein RP/EB family member 1.
- Clonality:
- Polyclonal
- Concentration:
- 0.5 mg/ml
- Extra Details:
- Plus-end tracking protein (+TIP) that binds to the plus-end of microtubules and regulates the dynamics of the microtubule cytoskeleton (PubMed:12388762; PubMed:16109370; PubMed:19632184; PubMed:21646404; PubMed:28726242; PubMed:28814570). Promotes cytoplasmic microtubule nucleation and elongation (PubMed:12388762; PubMed:16109370; PubMed:19632184; PubMed:21646404; PubMed:28726242; PubMed:28814570). May be involved in spindle function by stabilizing microtubules and anchoring them at centrosomes (PubMed:12388762). Also acts as a regulator of minus-end microtubule organization: interacts with the complex formed by AKAP9 and PDE4DIP; leading to recruit CAMSAP2 to the Golgi apparatus; thereby tethering non-centrosomal minus-end microtubules to the Golgi; an important step for polarized cell movement (PubMed:28814570). Promotes elongation of CAMSAP2-decorated microtubule stretches on the minus-end of microtubules (PubMed:28814570). Acts as a regulator of autophagosome transport via interaction with CAMSAP2 (PubMed:28726242). May play a role in cell migration (By similarity).
- Gene Details:
- microtubule associated protein RP/EB family member 1
- Host:
- Rabbit
- Immunogen:
- Range: Ala2 - Tyr268
- Isotype:
- IgG
- Molecular Weight:
- 30 kDa
- Protein Details:
- Microtubule-associated protein RP/EB family member 1
- Purification:
- Affinity Purified; Protein A Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2Â[o]C to 8Â[o]C|-20Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
