MAPK7 Antibody
Product Sizes
100ul
£326.00
OACD05436-100UL
1ml
£912.00
OACD05436-1ML
About this Product
- SKU:
- OACD05436
- Additional Names:
- b2b2346C;b2b2346Clo;big MAP kinase 1;BMK1;BMK-1;ERK;ERK5;Erk5-;ERK-5;Erk5-T;extracellular signal-regulated kinase 5;MAPK 7;mitogen-activated protein kinase 7;PRKM7.
- Clonality:
- Polyclonal
- Concentration:
- 0.5 mg/ml
- Extra Details:
- Plays a role in various cellular processes such as proliferation; differentiation and cell survival. The upstream activator of MAPK7 is the MAPK kinase MAP2K5. Upon activation; it translocates to the nucleus and phosphorylates various downstream targets including MEF2C. EGF activates MAPK7 through a Ras-independent and MAP2K5-dependent pathway. May have a role in muscle cell differentiation. May be important for endothelial function and maintenance of blood vessel integrity. MAP2K5 and MAPK7 interact specifically with one another and not with MEK1/ERK1 or MEK2/ERK2 pathways. Phosphorylates SGK1 at Ser-78 and this is required for growth factor-induced cell cycle progression (By similarity). Involved in the regulation of p53/TP53 by disrupting the PML-MDM2 interaction (By similarity).
- Gene Details:
- mitogen-activated protein kinase 7
- Host:
- Rabbit
- Immunogen:
- Range: Pro185 - Met419
- Isotype:
- IgG
- Molecular Weight:
- 56 kDa
- Protein Details:
- Mitogen-activated protein kinase 7
- Purification:
- Affinity Purified; Protein A Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2Â[o]C to 8Â[o]C|-20Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
