CD300LF Antibody
Product Sizes
100ul
£326.00
OACD04838-100UL
1ml
£912.00
OACD04838-1ML
About this Product
- SKU:
- OACD04838
- Additional Names:
- CD300 antigen like family member F;CD300 antigen-like family member F;CLIM1;CLM1;CLM-1;CMRF35-like molecule 1;CMRF-35-like molecule 1;DC-derived Ig-like receptor 2;DIg;Digr2;F730004D16Rik;IgSF;IgSF13;IRE;IREM1;leukocyte mono-Ig-like receptor 3;LM;LMIR3;MAIR-5;MAIR-V;myeloid-associated immunoglobulin-like receptor 5;Pi;Pigr3.
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- Acts as an inhibitory receptor for myeloid cells and mast cells (PubMed:17438331). Positively regulates the phagocytosis of apoptotic cells (efferocytosis) via phosphatidylserine (PS) recognition; recognizes and binds PS as a ligand which is expressed on the surface of apoptotic cells (PubMed:21865548). Plays an important role in the maintenance of immune homeostasis; by promoting macrophage-mediated efferocytosis and by inhibiting dendritic cell-mediated efferocytosis (PubMed:26768664). Negatively regulates Fc epsilon receptor-dependent mast cell activation and allergic responses via binding to ceramide which acts as a ligand (PubMed:23123064). May act as a coreceptor for interleukin 4 (IL-4). Associates with and regulates IL-4 receptor alpha-mediated responses by augmenting IL-4- and IL-13-induced signaling (PubMed:26124135). Negatively regulates the Toll-like receptor (TLR) signaling mediated by MYD88 and TRIF through activation of PTPN6/SHP-1 and PTPN11/SHP-2 (By similarity). Inhibits osteoclast formation (PubMed:14662855). Induces macrophage cell death upon engagement (PubMed:18097021).
- Gene Details:
- CD300 molecule like family member F
- Host:
- Rabbit
- Immunogen:
- Recombinant CD300LF (Ser45 - Ile310) expressed in E.coli.
- Isotype:
- IgG
- Protein Details:
- CMRF35-like molecule 1
- Purification:
- Affinity Purified; Protein A Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2Â[o]C to 8Â[o]C|-20Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
