IPO8 Antibody
Product Sizes
100ul
£316.00
OACD04828-100UL
1ml
£868.00
OACD04828-1ML
About this Product
- SKU:
- OACD04828
- Additional Names:
- 6230418K12Rik;Abcc10;ATP-binding cassette; sub-family C (CFTR/MRP); member 10;C130009K11Rik;imp8;importin-8;MRP7;Om;OM-;Om1;OM-1;oocyte maturation 1;Ra;ran-binding protein 8;Ranbp8.
- Clonality:
- Polyclonal
- Concentration:
- 0.5 mg/ml
- Extra Details:
- Seems to function in nuclear protein import; either by acting as autonomous nuclear transport receptor or as an adapter-like protein in association with the importin-beta subunit KPNB1. Acting autonomously; is thought to serve itself as receptor for nuclear localization signals (NLS) and to promote translocation of import substrates through the nuclear pore complex (NPC) by an energy requiring; Ran-dependent mechanism. At the nucleoplasmic side of the NPC; Ran binds to importin; the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus. In vitro mediates the nuclear import of SRP19 (By similarity).
- Gene Details:
- importin 8
- Host:
- Rabbit
- Immunogen:
- Range: Tyr417 - Val622
- Isotype:
- IgG
- Molecular Weight:
- 112 kDa
- Protein Details:
- Importin-8
- Purification:
- Affinity Purified; Protein A Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2Â[o]C to 8Â[o]C|-20Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
