NFKBIZ Antibody
Product Sizes
100ul
£333.00
OACD04537-100UL
1ml
£933.00
OACD04537-1ML
About this Product
- SKU:
- OACD04537
- Additional Names:
- Ikappa B-zeta variant 3;ikappaBzeta;IkappaB-zeta;I-kappa-B-zeta;IKBZ;ikB-zeta;IL-1 inducible nuclear ankyrin-repeat protein;INAP;MAIL;molecule possessing ankyrin repeats induced by lipopolysaccharide;NF-kappa-B inhibitor zeta;nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor; zeta.
- Clonality:
- Polyclonal
- Concentration:
- 0.98 mg/ml
- Extra Details:
- Involved in regulation of NF-kappa-B transcription factor complexes. Inhibits NF-kappa-B activity without affecting its nuclear translocation upon stimulation. Inhibits DNA-binding of RELA and NFKB1/p50; and of the NF-kappa-B p65-p50 heterodimer and the NF-kappa-B p50-p50 homodimer. Seems also to activate NF-kappa-B-mediated transcription. In vitro; upon association with NFKB1/p50 has transcriptional activation activity and; together with NFKB1/p50 and RELA; is recruited to LCN2 promoters. Promotes transcription of LCN2 and DEFB4. Is recruited to IL-6 promoters and activates IL-6 but decreases TNF-alpha production in response to LPS. Seems to be involved in the induction of inflammatory genes activated through TLR/IL-1 receptor signaling. May promote apoptosis (By similarity). Involved in the induction of T helper 17 cells (Th17) differentiation upon recognition of antigen by T cell antigen receptor (TCR) (By similarity).
- Gene Details:
- NFKB inhibitor zeta
- Host:
- Rabbit
- Immunogen:
- Range: Val422 - Thr651
- Isotype:
- IgG
- Molecular Weight:
- 64 kDa
- Protein Details:
- NF-kappa-B inhibitor zeta
- Purification:
- Affinity Purified; Protein A Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2Â[o]C to 8Â[o]C|-20Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
