HTRA1 Antibody
Product Sizes
100ul
£431.00
OACD04364-100UL
1ml
£1276.00
OACD04364-1ML
About this Product
- SKU:
- OACD04364
- Additional Names:
- b0161;ECK0160;Heat shock protein DegP;htrA;periplasmic serine endoprotease DegP;Protease Do;ptd.
- Clonality:
- Polyclonal
- Concentration:
- 0.5 mg/ml
- Extra Details:
- DegP acts as a chaperone at low temperatures but switches to a peptidase (heat shock protein) at higher temperatures (PubMed:10319814). Degrades transiently denatured and unfolded or misfolded proteins which accumulate in the periplasm following heat shock or other stress conditions (PubMed:16303867). DegP is efficient with Val-Xaa and Ile-Xaa peptide bonds; suggesting a preference for beta-branched side chain amino acids (PubMed:8830688). Only unfolded proteins devoid of disulfide bonds appear capable of being cleaved; thereby preventing non-specific proteolysis of folded proteins (PubMed:8830688). Its proteolytic activity is essential for the survival of cells at elevated temperatures (PubMed:7557477). It can degrade IciA; Ada; casein; globin and PapA. DegP shares specificity with DegQ (PubMed:8830688). DegP is also involved in the biogenesis of partially folded outer-membrane proteins (OMP).
- Gene Details:
- periplasmic serine endoprotease DegP
- Host:
- Rabbit
- Immunogen:
- Range: Lys304 - Lys442
- Isotype:
- IgG
- Protein Details:
- Periplasmic serine endoprotease DegP
- Purification:
- Affinity Purified; Protein A Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2Â[o]C to 8Â[o]C|-20Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
