HSPA2 Antibody
Product Sizes
100ul
£355.00
OACD04331-100UL
1ml
£1005.00
OACD04331-1ML
About this Product
- SKU:
- OACD04331
- Additional Names:
- heat shock 70kDa protein 2;heat shock protein 2;heat shock protein 70.2;heat shock protein alpha 2;heat shock protein family A member 2;heat shock-related 70 kDa protein 2;Hspt70;HST;Hst70;Testis-specific heat shock protein-related;testis-specific heat shock protein-related gene hst70.
- Clonality:
- Polyclonal
- Concentration:
- 0.5 mg/ml
- Extra Details:
- Molecular chaperone implicated in a wide variety of cellular processes; including protection of the proteome from stress; folding and transport of newly synthesized polypeptides; activation of proteolysis of misfolded proteins and the formation and dissociation of protein complexes. Plays a pivotal role in the protein quality control system; ensuring the correct folding of proteins; the re-folding of misfolded proteins and controlling the targeting of proteins for subsequent degradation. This is achieved through cycles of ATP binding; ATP hydrolysis and ADP release; mediated by co-chaperones. In the ATP-bound form; it has a low affinity for substrate proteins. However; upon hydrolysis of the ATP to ADP; it undergoes a conformational change that increases its affinity for substrate proteins. It goes through repeated cycles of ATP hydrolysis and nucleotide exchange; which permits cycles of substrate binding and release. Plays a role in spermatogenesis. In association with SHCBP1L may participate in the maintenance of spindle integrity during meiosis in male germ cells.
- Gene Details:
- heat shock protein family A (Hsp70) member 2
- Host:
- Rabbit
- Immunogen:
- Range: Met1 - Asp633
- Isotype:
- IgG
- Molecular Weight:
- 70 kDa
- Protein Details:
- Heat shock-related 70 kDa protein 2
- Purification:
- Affinity Purified; Protein A Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2Â[o]C to 8Â[o]C|-20Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
