GSAP Antibody
Product Sizes
100ul
£359.00
OACD04022-100UL
1ml
£1016.00
OACD04022-1ML
About this Product
- SKU:
- OACD04022
- Additional Names:
- gamma-secretase-activating protein;pigeon homolog;PION;protein pigeon homolog.
- Clonality:
- Polyclonal
- Concentration:
- 0.5 mg/ml
- Extra Details:
- Regulator of gamma-secretase activity; which specifically activates the production of amyloid-beta protein (amyloid-beta protein 40 and amyloid-beta protein 42); without affecting the cleavage of other gamma-secretase targets such has Notch. The gamma-secretase complex is an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (amyloid-beta precursor protein). Specifically promotes the gamma-cleavage of APP CTF-alpha (also named APP-CTF) by the gamma-secretase complex to generate amyloid-beta; while it reduces the epsilon-cleavage of APP CTF-alpha; leading to a low production of AICD.
- Gene Details:
- gamma-secretase activating protein
- Host:
- Rabbit
- Immunogen:
- Range: Asp616 - Leu854
- Isotype:
- IgG
- Molecular Weight:
- 29 kDa
- Protein Details:
- Gamma-secretase-activating protein
- Purification:
- Affinity Purified; Protein A Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2Â[o]C to 8Â[o]C|-20Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
