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Antibodies

EIF4EBP1 Antibody

Product Sizes
100ul
£359.00
OACD03199-100UL
1ml
£1020.00
OACD03199-1ML
About this Product
SKU:
OACD03199
Additional Names:
4EBP1;4E-BP1;BP-1;eIF4E-binding protein 1;eukaryotic translation initiation factor 4E-binding protein 1;PHAS-I;phosphorylated heat- and acid-stable protein regulated by insulin 1.
Clonality:
Polyclonal
Concentration:
0.5 mg/ml
Extra Details:
Repressor of translation initiation that regulates EIF4E activity by preventing its assembly into the eIF4F complex: hypophosphorylated form competes with EIF4G1/EIF4G3 and strongly binds to EIF4E; leading to repress translation. In contrast; hyperphosphorylated form dissociates from EIF4E; allowing interaction between EIF4G1/EIF4G3 and EIF4E; leading to initiation of translation. Mediates the regulation of protein translation by hormones; growth factors and other stimuli that signal through the MAP kinase and mTORC1 pathways.
Gene Details:
eukaryotic translation initiation factor 4E binding protein 1
Host:
Rabbit
Immunogen:
Range: Ser2 - Ile118
Isotype:
IgG
Molecular Weight:
13 kDa
Protein Details:
Eukaryotic translation initiation factor 4E-binding protein 1
Purification:
Affinity Purified; Protein A Purified
Shipping Conditions:
Blue Ice
Storage Conditions:
2Â[o]C to 8Â[o]C|-20Â[o]C
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody