EIF4EBP1 Antibody
Product Sizes
100ul
£366.00
OACD03197-100UL
1ml
£1042.00
OACD03197-1ML
About this Product
- SKU:
- OACD03197
- Additional Names:
- 4e-bp;4e-bp1;AA959816;eIF4E-binding protein 1;eukaryotic translation initiation factor 4E-binding protein 1;PH;PHAS-I;phosphorylated heat- and acid-stable protein regulated by insulin 1.
- Clonality:
- Polyclonal
- Concentration:
- 0.39 mg/ml
- Extra Details:
- Repressor of translation initiation that regulates EIF4E activity by preventing its assembly into the eIF4F complex: hypophosphorylated form competes with EIF4G1/EIF4G3 and strongly binds to EIF4E; leading to repress translation. In contrast; hyperphosphorylated form dissociates from EIF4E; allowing interaction between EIF4G1/EIF4G3 and EIF4E; leading to initiation of translation (By similarity). Mediates the regulation of protein translation by hormones; growth factors and other stimuli that signal through the MAP kinase and mTORC1 pathways (PubMed:7629182).
- Gene Details:
- eukaryotic translation initiation factor 4E binding protein 1
- Host:
- Rabbit
- Immunogen:
- Range: Ser2 - Ile117
- Isotype:
- IgG
- Molecular Weight:
- 12 kDa
- Protein Details:
- Eukaryotic translation initiation factor 4E-binding protein 1
- Purification:
- Affinity Purified; Protein A Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2Â[o]C to 8Â[o]C|-20Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
