EIF3A Antibody
Product Sizes
100ul
£326.00
OACD03196-100UL
1ml
£912.00
OACD03196-1ML
About this Product
- SKU:
- OACD03196
- Additional Names:
- A830012B05Rik;centrosomin;Cs;Csma;Eif;Eif3;eIF3 p167;eIF3 p180;eIF3 p185;Eif3s;Eif3s10;eIF-3-theta;Eukaryotic translation initiation factor 3 subunit 10;EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT 10 (EIF-3 THETA) (EIF3 P167) (EIF3 P180) (EIF3 P185) (P162 PROTEIN) (CENTROSOMIN);eukaryotic translation initiation factor 3 subunit A;eukaryotic translation initiation factor 3; subunit 10 (theta);mKIAA0139;p162.
- Clonality:
- Polyclonal
- Concentration:
- 0.5 mg/ml
- Extra Details:
- RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex; which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1; eIF-1A; eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation; including cell cycling; differentiation and apoptosis; and uses different modes of RNA stem-loop binding to exert either translational activation or repression.
- Gene Details:
- eukaryotic translation initiation factor 3; subunit A
- Host:
- Rabbit
- Immunogen:
- Range: Glu622 - Val848
- Isotype:
- IgG
- Molecular Weight:
- 162 kDa
- Protein Details:
- Eukaryotic translation initiation factor 3 subunit A
- Purification:
- Affinity Purified; Protein A Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2Â[o]C to 8Â[o]C|-20Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
