DPP4 Antibody
Product Sizes
100ul
£316.00
OACD03098-100UL
1ml
£868.00
OACD03098-1ML
About this Product
- SKU:
- OACD03098
- Additional Names:
- Cd26;dipeptidyl peptidase 4;dipeptidyl peptidase IV;Dpp;DPP IV;Dpp-4;T-cell activation antigen CD26;THA;THAM;thymocyte-activating molecule.
- Clonality:
- Polyclonal
- Concentration:
- 0.5 mg/ml
- Extra Details:
- Cell surface glycoprotein receptor involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Acts as a positive regulator of T-cell coactivation; by binding at least ADA; CAV1; IGF2R; and PTPRC. Its binding to CAV1 and CARD11 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Its interaction with ADA also regulates lymphocyte-epithelial cell adhesion. In association with FAP is involved in the pericellular proteolysis of the extracellular matrix (ECM); the migration and invasion of endothelial cells into the ECM. May be involved in the promotion of lymphatic endothelial cells adhesion; migration and tube formation. When overexpressed; enhanced cell proliferation; a process inhibited by GPC3. Acts also as a serine exopeptidase with a dipeptidyl peptidase activity that regulates various physiological processes by cleaving peptides in the circulation; including many chemokines; mitogenic growth factors; neuropeptides and peptide hormones. Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline.
- Gene Details:
- dipeptidylpeptidase 4
- Host:
- Rabbit
- Immunogen:
- Recombinant CD26 (Ser29~Arg178) expressed in E.coli
- Isotype:
- IgG
- Molecular Weight:
- 87 kDa
- Protein Details:
- Dipeptidyl peptidase 4
- Purification:
- Affinity Purified; Protein A Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2Â[o]C to 8Â[o]C|-20Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
