CX3CL1 Antibody
Product Sizes
100ul
£311.00
OACD02885-100UL
1ml
£853.00
OACD02885-1ML
About this Product
- SKU:
- OACD02885
- Additional Names:
- ABCD-3;C3Xkine;chemokine (C-X3-C motif) ligand 1;CX3C membrane-anchored chemokine;C-X3-C motif chemokine 1;CXC3;CXC3C;fractalkine;neurotactin;NTN;NTT;SCYD1;small inducible cytokine subfamily D (Cys-X3-Cys); member 1 (fractalkine; neurotactin);small inducible cytokine subfamily D (Cys-X3-Cys); member-1;small-inducible cytokine D1.
- Clonality:
- Polyclonal
- Concentration:
- 0.5 mg/ml
- Extra Details:
- Acts as a ligand for both CX3CR1 and integrins. Binds to CX3CR1 (PubMed:23125415; PubMed:9931005; PubMed:21829356). Binds to integrins ITGAV:ITGB3 and ITGA4:ITGB1. Can activate integrins in both a CX3CR1-dependent and CX3CR1-independent manner. In the presence of CX3CR1; activates integrins by binding to the classical ligand-binding site (site 1) in integrins. In the absence of CX3CR1; binds to a second site (site 2) in integrins which is distinct from site 1 and enhances the binding of other integrin ligands to site 1 (PubMed:23125415; PubMed:24789099). The soluble form is chemotactic for T-cells and monocytes and not for neutrophils. The membrane-bound form promotes adhesion of those leukocytes to endothelial cells. May play a role in regulating leukocyte adhesion and migration processes at the endothelium (PubMed:9024663; PubMed:9177350).
- Gene Details:
- C-X3-C motif chemokine ligand 1
- Host:
- Rabbit
- Immunogen:
- Range: Gln25 - Pro332
- Isotype:
- IgG
- Molecular Weight:
- 42 kDa
- Protein Details:
- Fractalkine
- Purification:
- Affinity Purified; Protein A Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2Â[o]C to 8Â[o]C|-20Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
