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Antibodies

CLEC4C Antibody

Product Sizes
100ul
£322.00
OACD02567-100UL
1ml
£890.00
OACD02567-1ML
About this Product
SKU:
OACD02567
Additional Names:
BDCA2;BDCA-2;Blood dendritic cell antigen 2;blood dendritic cell antigen 2 protein;CD303;CLECSF11;CLECSF7;C-type (calcium dependent; carbohydrate-recognition domain) lectin; superfamily member 11;C-type (calcium dependent; carbohydrate-recognition domain) lectin; superfamily member 7;C-type lectin domain family 4 member C;C-type lectin superfamily member 7;dendritic cell lectin b;dendritic lectin;DLEC;HECL;PRO34150.
Clonality:
Polyclonal
Concentration:
0.5 mg/ml
Extra Details:
Lectin-type cell surface receptor which may play a role in antigen capturing by dendritic cells (PubMed:11748283; PubMed:21880719; PubMed:25995448). Specifically recognizes non-sialylated galactose-terminated biantennary glycans containing the trisaccharide epitope Gal(beta1-3/4)GlcNAc(beta1-2)Man (PubMed:21880719; PubMed:25995448). Binds to serum IgG (PubMed:25995448). Efficiently targets ligand into antigen-processing and peptide-loading compartments for presentation to T-cells (PubMed:11748283). May mediate potent inhibition of induction of IFN-alpha/beta expression in plasmacytoid dendritic cells (PubMed:11748283; PubMed:21880719). May act as a signaling receptor that activates protein-tyrosine kinases and mobilizes intracellular calcium (PubMed:11748283).
Gene Details:
C-type lectin domain family 4 member C
Host:
Rabbit
Immunogen:
Range: Glu5 - Ile183
Isotype:
IgG
Molecular Weight:
21 kDa
Protein Details:
C-type lectin domain family 4 member C
Purification:
Affinity Purified; Protein A Purified
Shipping Conditions:
Blue Ice
Storage Conditions:
2Â[o]C to 8Â[o]C|-20Â[o]C
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody