BRD8 Antibody
Product Sizes
100ul
£344.00
OACD02030-100UL
1ml
£955.00
OACD02030-1ML
About this Product
- SKU:
- OACD02030
- Additional Names:
- 2610007E11Rik;4432404P07Rik;bromodomain-containing protein 8;p12;S;SMAP.
- Clonality:
- Polyclonal
- Concentration:
- 0.5 mg/ml
- Extra Details:
- May act as a coactivator during transcriptional activation by hormone-activated nuclear receptors (NR). Stimulates transcriptional activation by AR/DHTR; ESR1/NR3A1; RXRA/NR2B1 and THRB/ERBA2. Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction; tumor suppressor mediated growth arrest and replicative senescence; apoptosis; and DNA repair. NuA4 may also play a direct role in DNA repair when recruited to sites of DNA damage. Component of a SWR1-like complex that specifically mediates the removal of histone H2A.Z/H2AFZ from the nucleosome.
- Gene Details:
- bromodomain containing 8
- Host:
- Rabbit
- Immunogen:
- Range: Ala797 - Lys951
- Isotype:
- IgG
- Molecular Weight:
- 95 kDa
- Protein Details:
- Bromodomain-containing protein 8
- Purification:
- Affinity Purified; Protein A Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2Â[o]C to 8Â[o]C|-20Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
