ARG2 Antibody
Product Sizes
100ul
£355.00
OACD01787-100UL
1ml
£1005.00
OACD01787-1ML
About this Product
- SKU:
- OACD01787
- Additional Names:
- AII type II arginase;arginase II;arginase type II;arginase-2; mitochondrial;kidney-type arginase;non-hepatic arginase;type II arginase.
- Clonality:
- Polyclonal
- Concentration:
- 0.5 mg/ml
- Extra Details:
- May play a role in the regulation of extra-urea cycle arginine metabolism and also in down-regulation of nitric oxide synthesis. Extrahepatic arginase functions to regulate L-arginine bioavailability to nitric oxid synthase (NOS). Arginine metabolism is a critical regulator of innate and adaptive immune responses. Seems to be involved in negative regulation of the survival capacity of activated T cells. May suppress inflammation-related signaling in asthmatic airway epithelium. May play a role in promoting prenatal immune suppression. Regulates RPS6KB1 signaling; which promotes endothelial cell senescence and inflammation and implicates NOS3/eNOS dysfunction. Can inhibit endothelial autophagy independently of its enzymatic activity implicating mTORC2 signaling. Involved in vascular smooth muscle cell senescence and apoptosis independently of its enzymatic activity.
- Gene Details:
- arginase 2
- Host:
- Rabbit
- Immunogen:
- Range: Val23 - Ile354
- Isotype:
- IgG
- Molecular Weight:
- 39 kDa
- Protein Details:
- Arginase-2; mitochondrial
- Purification:
- Affinity Purified; Protein A Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2Â[o]C to 8Â[o]C|-20Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
