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Antibodies

APOO Antibody

Product Sizes
100ul
£333.00
OACD01763-100UL
1ml
£933.00
OACD01763-1ML
About this Product
SKU:
OACD01763
Additional Names:
Apolipoprotein O;brain my025;FAM121B;family with sequence similarity 121B;Mic23;MIC26;MICOS complex subunit MIC23;MICOS complex subunit MIC26;MICOS26;mitochondrial contact site and cristae organizing system subunit 26;My025;Protein FAM121B.
Clonality:
Polyclonal
Concentration:
0.5 mg/ml
Extra Details:
Component of the MICOS complex; a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions; inner membrane architecture; and formation of contact sites to the outer membrane. Plays a crucial role in crista junction formation and mitochondrial function (PubMed:25764979). Can promote cardiac lipotoxicity by enhancing mitochondrial respiration and fatty acid metabolism in cardiac myoblasts (PubMed:24743151). Promotes cholesterol efflux from macrophage cells. Detected in HDL; LDL and VLDL. Secreted by a microsomal triglyceride transfer protein (MTTP)-dependent mechanism; probably as a VLDL-associated protein that is subsequently transferred to HDL (PubMed:16956892).
Gene Details:
apolipoprotein O
Host:
Rabbit
Immunogen:
Range: Lys26 - Lys198
Isotype:
IgG
Molecular Weight:
20 kDa
Protein Details:
MICOS complex subunit MIC26
Purification:
Affinity Purified; Protein A Purified
Shipping Conditions:
Blue Ice
Storage Conditions:
2Â[o]C to 8Â[o]C|-20Â[o]C
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody