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Antibodies

APLN Antibody

Product Sizes
100ul
£355.00
OACD01702-100UL
1ml
£1005.00
OACD01702-1ML
About this Product
SKU:
OACD01702
Additional Names:
Apel;apelin;apelin; AGTRL1 ligand;APJ endogenous ligand.
Clonality:
Polyclonal
Concentration:
0.5 mg/ml
Extra Details:
Endogenous ligand for the apelin receptor (APLNR) (PubMed:11336787; PubMed:11359874; PubMed:26611206). Drives internalization of the apelin receptor (PubMed:11359874). Apelin-36 dissociates more hardly than (pyroglu)apelin-13 from APLNR (PubMed:11336787). Hormone involved in the regulation of cardiac precursor cell movements during gastrulation and heart morphogenesis (By similarity). Has an inhibitory effect on cytokine production in response to T-cell receptor/CD3 cross-linking; the oral intake of apelin in the colostrum and the milk might therefore modulate immune responses in neonates (By similarity). Plays a role in early coronary blood vessels formation (By similarity). Mediates myocardial contractility in an ERK1/2-dependent manner (PubMed:26611206). May also have a role in the central control of body fluid homeostasis by influencing vasopressin release and drinking behavior (PubMed:10617103; PubMed:11359874).
Gene Details:
apelin
Host:
Rabbit
Immunogen:
Range: Ala19 - Phe77
Isotype:
IgG
Protein Details:
Apelin
Purification:
Affinity Purified; Protein A Purified
Shipping Conditions:
Blue Ice
Storage Conditions:
2Â[o]C to 8Â[o]C|-20Â[o]C
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody