ADCY6 Antibody
Product Sizes
100ul
£326.00
OACD01433-100UL
1ml
£912.00
OACD01433-1ML
About this Product
- SKU:
- OACD01433
- Additional Names:
- AC;AC6;adenylate cyclase type 6;adenylate cyclase type VI;adenylyl cyclase 6;ATP pyrophosphate-lyase 6;ca(2+)-inhibitable adenylyl cyclase;mKIAA0422.
- Clonality:
- Polyclonal
- Concentration:
- 0.5 mg/ml
- Extra Details:
- Catalyzes the formation of the signaling molecule cAMP downstream of G protein-coupled receptors (PubMed:18071070; PubMed:24363043). Functions in signaling cascades downstream of beta-adrenergic receptors in the heart and in vascular smooth muscle cells (PubMed:18071070). Functions in signaling cascades downstream of the vasopressin receptor in the kidney and has a role in renal water reabsorption (PubMed:20466003; PubMed:20864687). Functions in signaling cascades downstream of PTH1R and plays a role in regulating renal phosphate excretion (PubMed:24854272). Functions in signaling cascades downstream of the VIP and SCT receptors in pancreas and contributes to the regulation of pancreatic amylase and fluid secretion (PubMed:23753526). Signaling mediates cAMP-dependent activation of protein kinase PKA and promotes increased phosphorylation of various proteins; including AKT (PubMed:18071070; PubMed:23753526). Plays a role in regulating cardiac sarcoplasmic reticulum Ca(2+) uptake and storage; and is required for normal heart ventricular contractibility (PubMed:18071070). May contribute to normal heart function (PubMed:18071070; PubMed:20359598). Mediates vasodilatation after activation of beta-adrenergic receptors by isoproterenol (By similarity). Contributes to bone cell responses to mechanical stimuli (PubMed:20371630; PubMed:24277577).
- Gene Details:
- adenylate cyclase 6
- Host:
- Rabbit
- Immunogen:
- Range: Gln314 - Asn501
- Isotype:
- IgG
- Molecular Weight:
- 130 kDa
- Protein Details:
- Adenylate cyclase type 6
- Purification:
- Affinity Purified; Protein A Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2Â[o]C to 8Â[o]C|-20Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
