ABCA4 Antibody
Product Sizes
100ul
£333.00
OACD01318-100UL
1ml
£933.00
OACD01318-1ML
About this Product
- SKU:
- OACD01318
- Additional Names:
- ABC10;ABCR;ARMD2;ATP binding cassette transporter;ATP-binding cassette sub-family A member 4;ATP-binding cassette transporter; retinal-specific;ATP-binding cassette; sub-family A (ABC1); member 4;ATP-binding transporter; retina-specific;CORD3;FFM;photoreceptor rim protein;retinal-specific ATP-binding cassette transporter;retinal-specific phospholipid-transporting ATPase ABCA4;retina-specific ABC transporter;RIM ABC transporter;RIM protein;RMP;RP19;stargardt disease protein;STGD;STGD1.
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- In the visual cycle; acts as an inward-directed retinoid flipase; retinoid substrates imported by ABCA4 from the extracellular or intradiscal (rod) membrane surfaces to the cytoplasmic membrane surface are all-trans-retinaldehyde (ATR) and N-retinyl-phosphatidyl-ethanolamine (NR-PE). Once transported to the cytoplasmic surface; ATR is reduced to vitamin A by trans-retinol dehydrogenase (tRDH) and then transferred to the retinal pigment epithelium (RPE) where it is converted to 11-cis-retinal. May play a role in photoresponse; removing ATR/NR-PE from the extracellular photoreceptor surfaces during bleach recovery.
- Gene Details:
- ATP binding cassette subfamily A member 4
- Host:
- Rabbit
- Immunogen:
- Recombinant ABCA4 (Gly1398~Asn1727) expressed in E.coli
- Isotype:
- IgG
- Molecular Weight:
- 256 kDa
- Protein Details:
- Retinal-specific ATP-binding cassette transporter
- Purification:
- Affinity Purified; Protein A Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2Â[o]C to 8Â[o]C|-20Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
