ACD Antibody
Product Sizes
100ul
£355.00
OACD01237-100UL
1ml
£1005.00
OACD01237-1ML
About this Product
- SKU:
- OACD01237
- Additional Names:
- adrenocortical dysplasia homolog;adrenocortical dysplasia protein homolog.
- Clonality:
- Polyclonal
- Concentration:
- 0.5 mg/ml
- Extra Details:
- Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded TTAGGG repeats added by telomerase and protects chromosome ends. Without its protective activity; telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways. Promotes binding of POT1 to single-stranded telomeric DNA. Modulates the inhibitory effects of POT1 on telomere elongation. The ACD-POT1 heterodimer enhances telomere elongation by recruiting telomerase to telomeres and increasing its processivity. May play a role in organogenesis.
- Gene Details:
- ACD; shelterin complex subunit and telomerase recruitment factor
- Host:
- Rabbit
- Immunogen:
- Range: Asn147 - Glu342
- Isotype:
- IgG
- Molecular Weight:
- 46 kDa
- Protein Details:
- Adrenocortical dysplasia protein homolog
- Purification:
- Affinity Purified; Protein A Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2Â[o]C to 8Â[o]C|-20Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
