DNAJC2 Antibody
Product Sizes
100ul
£333.00
OACD01154-100UL
1ml
£933.00
OACD01154-1ML
About this Product
- SKU:
- OACD01154
- Additional Names:
- DnaJ (Hsp40) homolog; subfamily C; member 2;dnaJ homolog subfamily C member 2;M-phase phosphoprotein 11;MPHOSPH11;MPP11;ZRF1;ZUO1;zuotin-related factor 1.
- Clonality:
- Polyclonal
- Concentration:
- 0.5 mg/ml
- Extra Details:
- Acts both as a chaperone in the cytosol and as a chromatin regulator in the nucleus. When cytosolic; acts as a molecular chaperone: component of the ribosome-associated complex (RAC); a complex involved in folding or maintaining nascent polypeptides in a folding-competent state. In the RAC complex; stimulates the ATPase activity of the ribosome-associated pool of Hsp70-type chaperones HSPA14 that bind to the nascent polypeptide chain. When nuclear; mediates the switching from polycomb-repressed genes to an active state: specifically recruited at histone H2A ubiquitinated at 'Lys-119' (H2AK119ub); and promotes the displacement of the polycomb PRC1 complex from chromatin; thereby facilitating transcription activation. Specifically binds DNA sequence 5'-GTCAAGC-3'.
- Gene Details:
- DnaJ heat shock protein family (Hsp40) member C2
- Host:
- Rabbit
- Immunogen:
- Range: Lys442 - Lys621
- Isotype:
- IgG
- Molecular Weight:
- 66 kDa
- Protein Details:
- DnaJ homolog subfamily C member 2
- Purification:
- Affinity Purified; Protein A Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2Â[o]C to 8Â[o]C|-20Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
