ERLIN2 Antibody
Product Sizes
100ul
£359.00
OACD01012-100UL
1ml
£1020.00
OACD01012-1ML
About this Product
- SKU:
- OACD01012
- Additional Names:
- C8orf2;endoplasmic reticulum lipid raft-associated protein 2;epididymis secretory sperm binding protein;erlin-2;NET32;spastic paraplegia 18 (autosomal dominant);SPFH domain family; member 2;SPFH2;SPG18;stomatin-prohibitin-flotillin-HflC/K domain-containing protein 2.
- Clonality:
- Polyclonal
- Concentration:
- 0.5 mg/ml
- Extra Details:
- Component of the ERLIN1/ERLIN2 complex which mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1;4;5-trisphosphate receptors (IP3Rs) such as ITPR1 (PubMed:19240031; PubMed:17502376). Promotes sterol-accelerated ERAD of HMGCR probably implicating an AMFR/gp78-containing ubiquitin ligase complex (PubMed:21343306). Involved in regulation of cellular cholesterol homeostasis by regulation the SREBP signaling pathway. May promote ER retention of the SCAP-SREBF complex (PubMed:24217618).
- Gene Details:
- ER lipid raft associated 2
- Host:
- Rabbit
- Immunogen:
- Range: Pro47 - Asn339
- Isotype:
- IgG
- Molecular Weight:
- 17 kDa
- Protein Details:
- Erlin-2
- Purification:
- Affinity Purified; Protein A Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2Â[o]C to 8Â[o]C|-20Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
