SMUG1 Antibody
Product Sizes
100ul
£333.00
OACD00959-100UL
1ml
£933.00
OACD00959-1ML
About this Product
- SKU:
- OACD00959
- Additional Names:
- FDG;HMUDG;single-strand selective monofunctional uracil DNA glycosylase;UNG3.
- Clonality:
- Polyclonal
- Concentration:
- 0.5 mg/ml
- Extra Details:
- Recognizes base lesions in the genome and initiates base excision DNA repair. Acts as a monofunctional DNA glycosylase specific for uracil (U) residues in DNA with a preference for single-stranded DNA substrates. The activity is greater toward mismatches (U/G) compared to matches (U/A). Excises uracil (U); 5-formyluracil (fU) and uracil derivatives bearing an oxidized group at C5 [5-hydroxyuracil (hoU) and 5-hydroxymethyluracil (hmU)] in ssDNA and dsDNA; but not analogous cytosine derivatives (5-hydroxycytosine and 5-formylcytosine); nor other oxidized bases. The activity is damage-specific and salt-dependent. The substrate preference is the following: ssDNA > dsDNA (G pair) = dsDNA (A pair) at low salt concentration; and dsDNA (G pair) > dsDNA (A pair) > ssDNA at high salt concentration.
- Gene Details:
- single-strand-selective monofunctional uracil-DNA glycosylase 1
- Host:
- Rabbit
- Immunogen:
- Range: Met1 - Lys270
- Isotype:
- IgG
- Molecular Weight:
- 20 kDa
- Protein Details:
- Single-strand selective monofunctional uracil DNA glycosylase
- Purification:
- Affinity Purified; Protein A Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2Â[o]C to 8Â[o]C|-20Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
