TOPBP1 Antibody
Product Sizes
100ul
£333.00
OACD00782-100UL
1ml
£933.00
OACD00782-1ML
About this Product
- SKU:
- OACD00782
- Additional Names:
- DNA topoisomerase 2-binding protein 1;DNA topoisomerase II-beta-binding protein 1;DNA topoisomerase II-binding protein 1;Dpb11;TOP2BP1;topoisomerase (DNA) II binding protein 1.
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- Required for DNA replication. Plays a role in the rescue of stalled replication forks and checkpoint control. Binds double-stranded DNA breaks and nicks as well as single-stranded DNA. Recruits the SWI/SNF chromatin remodeling complex to E2F1-responsive promoters. Down-regulates E2F1 activity and inhibits E2F1-dependent apoptosis during G1/S transition and after DNA damage. Induces a large increase in the kinase activity of ATR (PubMed:16530042).
- Gene Details:
- DNA topoisomerase II binding protein 1
- Host:
- Rabbit
- Immunogen:
- Range: Met1 - Lys250
- Isotype:
- IgG
- Molecular Weight:
- 171 kDa
- Protein Details:
- DNA topoisomerase 2-binding protein 1
- Purification:
- Affinity Purified; Protein A Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2Â[o]C to 8Â[o]C|-20Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
