ERI1 Antibody
Product Sizes
100ul
£344.00
OACD00696-100UL
1ml
£955.00
OACD00696-1ML
About this Product
- SKU:
- OACD00696
- Additional Names:
- 3110010F15Rik;3'-5' exonuclease ERI1;3'-5' exoribonuclease 1;3'hexo;enhanced RNAi protein 1;Er;eri-1;eri-1 homolog;histone mRNA 3' end-specific exonuclease;histone mRNA 3'-exonuclease 1;Thex1;three prime histone mRNA exonuclease 1.
- Clonality:
- Polyclonal
- Concentration:
- 0.5 mg/ml
- Extra Details:
- RNA exonuclease that binds to the 3'-end of histone mRNAs and degrades them; suggesting that it plays an essential role in histone mRNA decay after replication. A 2' and 3'-hydroxyl groups at the last nucleotide of the histone 3'-end is required for efficient degradation of RNA substrates. Also able to degrade the 3'-overhangs of short interfering RNAs (siRNAs) in vitro; suggesting a possible role as regulator of RNA interference (RNAi). Binds with high affinity to the 3' side of the stem-loop structure and to the downstream cleavage product (DCP) of histone pre-mRNAs. Requires for binding the 5'-ACCCA-3' sequence present in stem-loop structure. Able to bind other mRNAs (By similarity). Required for 5.8S rRNA 3'-end processing. Also binds to 5.8s ribosomal RNA.
- Gene Details:
- exoribonuclease 1
- Host:
- Rabbit
- Immunogen:
- Range: Met1 - Lys345
- Isotype:
- IgG
- Molecular Weight:
- 39 kDa
- Protein Details:
- 3'-5' exoribonuclease 1
- Purification:
- Affinity Purified; Protein A Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2Â[o]C to 8Â[o]C|-20Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
