TOPBP1 Antibody
Product Sizes
100ul
£344.00
OACD00492-100UL
1ml
£955.00
OACD00492-1ML
About this Product
- SKU:
- OACD00492
- Additional Names:
- 1110031N14Rik;2810429C13Rik;AI256758;D430026L04Rik;DNA topoisomerase 2-binding protein 1;DNA topoisomerase II-beta-binding protein 1;DNA topoisomerase II-binding protein 1;mKIAA0259;topoisomerase (DNA) II beta binding protein.
- Clonality:
- Polyclonal
- Concentration:
- 0.5 mg/ml
- Extra Details:
- Required for DNA replication (By similarity). Plays a role in the rescue of stalled replication forks and checkpoint control (PubMed:14718568). Binds double-stranded DNA breaks and nicks as well as single-stranded DNA (By similarity). Recruits the SWI/SNF chromatin remodeling complex to E2F1-responsive promoters. Down-regulates E2F1 activity and inhibits E2F1-dependent apoptosis during G1/S transition and after DNA damage (By similarity). Induces a large increase in the kinase activity of ATR (By similarity).
- Gene Details:
- topoisomerase (DNA) II binding protein 1
- Host:
- Rabbit
- Immunogen:
- Range: Met1 - Pro246
- Isotype:
- IgG
- Molecular Weight:
- 169 kDa
- Protein Details:
- DNA topoisomerase 2-binding protein 1
- Purification:
- Affinity Purified; Protein A Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2Â[o]C to 8Â[o]C|-20Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
