HSPA1L Antibody
Product Sizes
100ul
£355.00
OACD00278-100UL
200ul
£463.00
OACD00278-200UL
1ml
£1009.00
OACD00278-1ML
About this Product
- SKU:
- OACD00278
- Additional Names:
- heat shock 70 kDa protein 1L;heat shock 70 kDa protein 1-like;heat shock 70 kDa protein 3;heat shock protein 1-like;heat shock protein 70;Heat shock protein 70-1l;HSP70.3;Hsp70-3.
- translate.label.attr.clone:
- 6#
- Clonality:
- Monoclonal
- Concentration:
- 0.25 mg/ml
- Extra Details:
- Molecular chaperone implicated in a wide variety of cellular processes; including protection of the proteome from stress; folding and transport of newly synthesized polypeptides; activation of proteolysis of misfolded proteins and the formation and dissociation of protein complexes. Plays a pivotal role in the protein quality control system; ensuring the correct folding of proteins; the re-folding of misfolded proteins and controlling the targeting of proteins for subsequent degradation. This is achieved through cycles of ATP binding; ATP hydrolysis and ADP release; mediated by co-chaperones. The affinity for polypeptides is regulated by its nucleotide bound state. In the ATP-bound form; it has a low affinity for substrate proteins. However; upon hydrolysis of the ATP to ADP; it undergoes a conformational change that increases its affinity for substrate proteins. It goes through repeated cycles of ATP hydrolysis and nucleotide exchange; which permits cycles of substrate binding and release. Positive regulator of PRKN translocation to damaged mitochondria.
- Gene Details:
- heat shock protein family A (Hsp70) member 1 like
- Host:
- Mouse
- Immunogen:
- <a href='//www.avivasysbio.com/hspa1l-recombinant-protein-opcd04017.html' target='_blank'>Hspa1l Recombinant Protein (OPCD04017)</a>
- Isotype:
- IgG2b Kappa
- Protein Details:
- Heat shock 70 kDa protein 1-like
- Purification:
- Protein A/G Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2Â[o]C to 8Â[o]C|-20Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
