ATG4C Antibody
Product Sizes
50ug
£305.00
OACA10626-50UG
100ug
£463.00
OACA10626-100UG
About this Product
- SKU:
- OACA10626
- Additional Names:
- APG4 autophagy 4 homolog C;APG4C;APG4-C;ATG4 autophagy related 4 homolog C;AUTL1;AUTL3;AUT-like 1; cysteine endopeptidase;AUT-like 3 cysteine endopeptidase;autophagin-3;autophagy-related cysteine endopeptidase 3;autophagy-related protein 4 homolog C;cysteine protease ATG4C;epididymis secretory sperm binding protein.
- Clonality:
- Polyclonal
- Conjugate:
- Unconjugated
- Extra Details:
- Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Is not essential for autophagy development under normal conditions but is required for a proper autophagic response under stressful conditions such as prolonged starvation (By similarity). Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3 and GABARAPL2; to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes; which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjugated forms.
- Gene Details:
- autophagy related 4C cysteine peptidase
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Cysteine protease ATG4C protein (419-448AA)
- Isotype:
- IgG
- Protein Details:
- Cysteine protease ATG4C
- Purity:
- >95%
- Purification:
- Protein G Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20Â[o]C or -80Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
