MYO7A Antibody
Product Sizes
50ug
£305.00
OACA10566-50UG
100ug
£463.00
OACA10566-100UG
About this Product
- SKU:
- OACA10566
- Additional Names:
- DFNA11;DFNB2;myosin VIIA (Usher syndrome 1B (autosomal recessive; severe));MYOVIIA;MYU7A;NSRD2;unconventional myosin-VIIa;USH1B.
- Clonality:
- Polyclonal
- Conjugate:
- Unconjugated
- Extra Details:
- Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails bind to membranous compartments; which are then moved relative to actin filaments. In the retina; plays an important role in the renewal of the outer photoreceptor disks. Plays an important role in the distribution and migration of retinal pigment epithelial (RPE) melanosomes and phagosomes; and in the regulation of opsin transport in retinal photoreceptors. In the inner ear; plays an important role in differentiation; morphogenesis and organization of cochlear hair cell bundles. Involved in hair-cell vesicle trafficking of aminoglycosides; which are known to induce ototoxicity (By similarity). Motor protein that is a part of the functional network formed by USH1C; USH1G; CDH23 and MYO7A that mediates mechanotransduction in cochlear hair cells. Required for normal hearing.
- Gene Details:
- myosin VIIA
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Unconventional myosin-VIIa protein (838-968AA)
- Isotype:
- IgG
- Protein Details:
- Unconventional myosin-VIIa
- Purity:
- >95%
- Purification:
- Protein G Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20Â[o]C or -80Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
