TRADD Antibody
Product Sizes
50ug
£305.00
OACA10565-50UG
100ug
£463.00
OACA10565-100UG
About this Product
- SKU:
- OACA10565
- Additional Names:
- Hs.89862;TNFR1-associated death domain protein;TNFRSF1A-associated via death domain;tumor necrosis factor receptor type 1 associated death domain protein;tumor necrosis factor receptor type 1-associated DEATH domain protein;tumor necrosis factor receptor-1-associated protein.
- Clonality:
- Polyclonal
- Conjugate:
- Unconjugated
- Concentration:
- Varies by lot. See vial for concentration.
- Extra Details:
- The nuclear form acts as a tumor suppressor by preventing ubiquitination and degradation of isoform p19ARF/ARF of CDKN2A by TRIP12: acts by interacting with TRIP12; leading to disrupt interaction between TRIP12 and isoform p19ARF/ARF of CDKN2A (By similarity). Adapter molecule for TNFRSF1A/TNFR1 that specifically associates with the cytoplasmic domain of activated TNFRSF1A/TNFR1 mediating its interaction with FADD. Overexpression of TRADD leads to two major TNF-induced responses; apoptosis and activation of NF-kappa-B.
- Gene Details:
- TNFRSF1A associated via death domain
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Tumor necrosis factor receptor type 1-associated DEATH domain protein (1-312AA)
- Isotype:
- IgG
- Protein Details:
- Tumor necrosis factor receptor type 1-associated DEATH domain protein
- Purity:
- >95%
- Purification:
- Protein G Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20Â[o]C or -80Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
