BCL2 Antibody
Product Sizes
50ug
£305.00
OACA10460-50UG
100ug
£463.00
OACA10460-100UG
About this Product
- SKU:
- OACA10460
- Additional Names:
- apoptosis regulator Bcl-2;B-cell CLL/lymphoma 2;Bcl-2;PPP1R50;protein phosphatase 1; regulatory subunit 50.
- Clonality:
- Polyclonal
- Conjugate:
- Unconjugated
- Extra Details:
- Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1). May attenuate inflammation by impairing NLRP1-inflammasome activation; hence CASP1 activation and IL1B release (PubMed:17418785).
- Gene Details:
- BCL2 apoptosis regulator
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Apoptosis regulator Bcl-2 protein (31-80AA)
- Isotype:
- IgG
- Protein Details:
- Apoptosis regulator Bcl-2
- Purity:
- >95%
- Purification:
- Protein G Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20Â[o]C or -80Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
