NUDT1 Antibody
Product Sizes
50ug
£305.00
OACA10375-50UG
100ug
£463.00
OACA10375-100UG
About this Product
- SKU:
- OACA10375
- Additional Names:
- 2-hydroxy-dATP diphosphatase;7;8-dihydro-8-oxoguanine triphosphatase;8-oxo-7;8-dihydrodeoxyguanosine triphosphatase;8-oxo-7;8-dihydroguanosine triphosphatase;8-oxo-dGTPase;MTH1;mutT human homolog 1;nucleoside diphosphate-linked moiety X motif 1;nucleoside diphosphate-linked moiety X-type motif 1;nudix (nucleoside diphosphate linked moiety X)-type motif 1;nudix motif 1.
- Clonality:
- Polyclonal
- Conjugate:
- Unconjugated
- Extra Details:
- Antimutagenic (PubMed:8226881; PubMed:7713500; PubMed:10608900). Plays a redundant role in sanitizing oxidized nucleotide pools; such as 8-oxo-dGTP pools (PubMed:28679043). Acts as a sanitizing enzyme for oxidized nucleotide pools; thus suppressing cell dysfunction and death induced by oxidative stress (PubMed:12857738; PubMed:24695224; PubMed:24695225). Hydrolyzes 8-oxo-dGTP; 8-oxo-dATP and 2-OH-dATP; thus preventing misincorporation of oxidized purine nucleoside triphosphates into DNA and subsequently preventing A:T to C:G and G:C to T:A transversions (PubMed:8226881; PubMed:10373420; PubMed:10608900; PubMed:11756418; PubMed:12857738; PubMed:16607562; PubMed:24695224; PubMed:24695225; PubMed:26999531; PubMed:28035004). Able to hydrolyze also the corresponding ribonucleotides; 2-OH-ATP; 8-oxo-GTP and 8-oxo-ATP (PubMed:10373420; PubMed:11139615). Does not play a role in U8 snoRNA decapping activity. Binds U8 snoRNA (By similarity).
- Gene Details:
- nudix hydrolase 1
- Host:
- Rabbit
- Immunogen:
- Recombinant Human 7;8-dihydro-8-oxoguanine triphosphatase protein (49-82AA)
- Isotype:
- IgG
- Protein Details:
- 7;8-dihydro-8-oxoguanine triphosphatase
- Purity:
- >95%
- Purification:
- Protein G Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20Â[o]C or -80Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
