EPHA5 Antibody
Product Sizes
50ug
£305.00
OACA10314-50UG
100ug
£463.00
OACA10314-100UG
About this Product
- SKU:
- OACA10314
- Additional Names:
- brain-specific kinase;CEK7;EHK1;EHK-1;EK7;EPH homology kinase 1;EPH-like kinase 7;ephrin type-A receptor 5;epididymis secretory sperm binding protein;HEK7;receptor protein-tyrosine kinase HEK7;TYRO4;tyrosine-protein kinase receptor EHK-1.
- Clonality:
- Polyclonal
- Conjugate:
- Unconjugated
- Extra Details:
- Receptor tyrosine kinase which binds promiscuously GPI-anchored ephrin-A family ligands residing on adjacent cells; leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Among GPI-anchored ephrin-A ligands; EFNA5 most probably constitutes the cognate/functional ligand for EPHA5. Functions as an axon guidance molecule during development and may be involved in the development of the retinotectal; entorhino-hippocampal and hippocamposeptal pathways. Together with EFNA5 plays also a role in synaptic plasticity in adult brain through regulation of synaptogenesis. In addition to its function in the nervous system; the interaction of EPHA5 with EFNA5 mediates communication between pancreatic islet cells to regulate glucose-stimulated insulin secretion (By similarity).
- Gene Details:
- EPH receptor A5
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Ephrin type-A receptor 5 protein (246-514AA)
- Isotype:
- IgG
- Protein Details:
- Ephrin type-A receptor 5
- Purity:
- >95%
- Purification:
- Protein G Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20Â[o]C or -80Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
