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Antibodies

CD79A Antibody

Product Sizes
50ug
£305.00
OACA10284-50UG
100ug
£463.00
OACA10284-100UG
About this Product
SKU:
OACA10284
Additional Names:
B-cell antigen receptor complex-associated protein alpha chain;CD79a antigen (immunoglobulin-associated alpha);CD79a molecule; immunoglobulin-associated alpha;IGA;ig-alpha;MB-1;MB-1 membrane glycoprotein;membrane-bound immunoglobulin-associated protein;surface IgM-associated protein.
Clonality:
Polyclonal
Conjugate:
Unconjugated
Extra Details:
Required in cooperation with CD79B for initiation of the signal transduction cascade activated by binding of antigen to the B-cell antigen receptor complex (BCR) which leads to internalization of the complex; trafficking to late endosomes and antigen presentation. Also required for BCR surface expression and for efficient differentiation of pro- and pre-B-cells. Stimulates SYK autophosphorylation and activation. Binds to BLNK; bringing BLNK into proximity with SYK and allowing SYK to phosphorylate BLNK. Also interacts with and increases activity of some Src-family tyrosine kinases. Represses BCR signaling during development of immature B-cells.
Gene Details:
CD79a molecule
Host:
Rabbit
Immunogen:
Recombinant Human B-cell antigen receptor complex-associated protein alpha chain protein (70-142AA)
Isotype:
IgG
Protein Details:
B-cell antigen receptor complex-associated protein alpha chain
Purity:
>95%
Purification:
Protein G Purified
Shipping Conditions:
Blue Ice
Storage Conditions:
-20Â[o]C or -80Â[o]C
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody