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Antibodies

ATG4B Antibody

Product Sizes
50ug
£305.00
OACA10273-50UG
100ug
£463.00
OACA10273-100UG
About this Product
SKU:
OACA10273
Additional Names:
APG4 autophagy 4 homolog B;APG4B;ATG4 autophagy related 4 homolog B;AUTL1;AUT-like 1 cysteine endopeptidase;autophagin-1;autophagy-related cysteine endopeptidase 1;autophagy-related protein 4 homolog B;cysteine protease ATG4B;hAPG4B.
Clonality:
Polyclonal
Conjugate:
Unconjugated
Extra Details:
Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3; GABARAPL1; GABARAPL2 and GABARAP; to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes; which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjugated forms.
Gene Details:
autophagy related 4B cysteine peptidase
Host:
Rabbit
Immunogen:
Recombinant Human Cysteine protease ATG4B protein (350-400AA)
Isotype:
IgG
Protein Details:
Cysteine protease ATG4B
Purity:
>95%
Purification:
Protein G Purified
Shipping Conditions:
Blue Ice
Storage Conditions:
-20Â[o]C or -80Â[o]C
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody