MCM8 Antibody
Product Sizes
50ug
£305.00
OACA10118-50UG
100ug
£463.00
OACA10118-100UG
About this Product
- SKU:
- OACA10118
- Additional Names:
- C20orf154;dJ967N21.5;DNA helicase MCM8;DNA replication licensing factor MCM8;MCM8 minichromosome maintenance deficient 8;Minichromosome maintenance 8;minichromosome maintenance complex component 8;POF10;REC homolog.
- Clonality:
- Polyclonal
- Conjugate:
- Unconjugated
- Extra Details:
- Component of the MCM8-MCM9 complex; a complex involved in homologous recombination repair following DNA interstrand cross-links and plays a key role during gametogenesis. The MCM8-MCM9 complex probably acts as a hexameric helicase downstream of the Fanconi anemia proteins BRCA2 and RAD51 and is required to process aberrant forks into homologous recombination substrates and to orchestrate homologous recombination with resection; fork stabilization and fork restart. May also play a non-essential for DNA replication: may be involved in the activation of the prereplicative complex (pre-RC) during G(1) phase by recruiting CDC6 to the origin recognition complex (ORC). Binds chromatin throughout the cell cycle.
- Gene Details:
- minichromosome maintenance 8 homologous recombination repair factor
- Host:
- Rabbit
- Immunogen:
- Recombinant Human DNA helicase MCM8 protein (1-67AA)
- Isotype:
- IgG
- Protein Details:
- DNA helicase MCM8
- Purity:
- >95%
- Purification:
- Protein G Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20Â[o]C or -80Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
