ATP8A2 Antibody
Product Sizes
50ug
£305.00
OACA10103-50UG
100ug
£463.00
OACA10103-100UG
About this Product
- SKU:
- OACA10103
- Additional Names:
- ATP;ATPase class I type 8A member 2;ATPase; aminophospholipid transporter; class I; type 8A; member 2;ATPase; aminophospholipid transporter-like; class I; type 8A; member 2;ATPIB;CAMRQ4;IB;ML-1;P4-ATPase flippase complex alpha subunit ATP8A2;phospholipid-transporting ATPase IB;probable phospholipid-transporting ATPase IB.
- Clonality:
- Polyclonal
- Conjugate:
- Unconjugated
- Extra Details:
- Catalytic component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules. Reconstituted to liposomes; the ATP8A2:TMEM30A flippase complex predomiminantly transports phosphatidylserine (PS) and to a lesser extent phosphatidylethanolamine (PE). Proposed to function in the generation and maintenance of phospholipid asymmetry in photoreceptor disk membranes and neuronal axon membranes. May be involved in vesicle trafficking in neuronal cells. Involved in regulation of neurite outgrowth; acting in synergy with TMEM30A. Required for normal visual and auditory function; involved in photoreceptor and inner ear spiral ganglion cell survival.
- Gene Details:
- ATPase phospholipid transporting 8A2
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Phospholipid-transporting ATPase IB protein (358-570AA)
- Isotype:
- IgG
- Protein Details:
- Phospholipid-transporting ATPase IB
- Purity:
- >95%
- Purification:
- Protein G Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20Â[o]C or -80Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
