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Antibodies

CYR61 Antibody

Product Sizes
50ug
£305.00
OACA10053-50UG
100ug
£463.00
OACA10053-100UG
About this Product
SKU:
OACA10053
Additional Names:
CCN family member 1;CYR61;cysteine rich angiogenic inducer 61;Cysteine-rich angiogenic inducer 61;cysteine-rich heparin-binding protein 61;cysteine-rich; anigogenic inducer; 61;GIG1;IBP-10;IGF-binding protein 10;IGFBP10;IGFBP-10;insulin-like growth factor-binding protein 10;protein CYR61;Protein GIG1.
Clonality:
Polyclonal
Conjugate:
Unconjugated
Extra Details:
Promotes cell proliferation; chemotaxis; angiogenesis and cell adhesion. Appears to play a role in wound healing by up-regulating; in skin fibroblasts; the expression of a number of genes involved in angiogenesis; inflammation and matrix remodeling including VEGA-A; VEGA-C; MMP1; MMP3; TIMP1; uPA; PAI-1 and integrins alpha-3 and alpha-5. CYR61-mediated gene regulation is dependent on heparin-binding. Down-regulates the expression of alpha-1 and alpha-2 subunits of collagen type-1. Promotes cell adhesion and adhesive signaling through integrin alpha-6/beta-1; cell migration through integrin alpha-v/beta-5 and cell proliferation through integrin alpha-v/beta-3.
Gene Details:
cellular communication network factor 1
Host:
Rabbit
Immunogen:
Recombinant Human Protein CYR61 protein (25-381AA)
Isotype:
IgG
Protein Details:
Protein CYR61
Purity:
>95%
Purification:
Protein G Purified
Shipping Conditions:
Blue Ice
Storage Conditions:
-20Â[o]C or -80Â[o]C
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody