APTX Antibody
Product Sizes
50ug
£305.00
OACA09978-50UG
100ug
£463.00
OACA09978-100UG
About this Product
- SKU:
- OACA09978
- Additional Names:
- AOA;AOA1;aprataxin;AXA1;EAOH;EOAHA;FHA-HIT;forkhead-associated domain histidine triad-like protein.
- Clonality:
- Polyclonal
- Conjugate:
- Unconjugated
- Extra Details:
- DNA-binding protein involved in single-strand DNA break repair; double-strand DNA break repair and base excision repair (PubMed:15380105; PubMed:15044383; PubMed:16964241; PubMed:17276982; PubMed:24362567). Resolves abortive DNA ligation intermediates formed either at base excision sites; or when DNA ligases attempt to repair non-ligatable breaks induced by reactive oxygen species (PubMed:16964241; PubMed:24362567). Catalyzes the release of adenylate groups covalently linked to 5'-phosphate termini; resulting in the production of 5'-phosphate termini that can be efficiently rejoined (PubMed:16964241; PubMed:17276982; PubMed:24362567). Also able to hydrolyze adenosine 5'-monophosphoramidate (AMP-NH(2)) and diadenosine tetraphosphate (AppppA); but with lower catalytic activity (PubMed:16547001). Likewise; catalyzes the release of 3'-linked guanosine (DNAppG) and inosine (DNAppI) from DNA; but has higher specific activity with 5'-linked adenosine (AppDNA) (By similarity).
- Gene Details:
- aprataxin
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Aprataxin protein (92-161AA)
- Isotype:
- IgG
- Protein Details:
- Aprataxin
- Purity:
- >95%
- Purification:
- Protein G Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20Â[o]C or -80Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
