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Antibodies

C2CD3 Antibody

Product Sizes
50ug
£305.00
OACA09901-50UG
100ug
£463.00
OACA09901-100UG
About this Product
SKU:
OACA09901
Additional Names:
C2 calcium dependent domain containing 3;C2 domain-containing protein 3;OFD14.
Clonality:
Polyclonal
Conjugate:
Unconjugated
Extra Details:
Component of the centrioles that acts as a positive regulator of centriole elongation (PubMed:24997988). Promotes assembly of centriolar distal appendage; a structure at the distal end of the mother centriole that acts as an anchor of the cilium; and is required for recruitment of centriolar distal appendages proteins CEP83; SCLT1; CEP89; FBF1 and CEP164. Not required for centriolar satellite integrity or RAB8 activation. Required for primary cilium formation (PubMed:23769972). Required for sonic hedgehog/SHH signaling and for proteolytic processing of GLI3.
Gene Details:
C2 domain containing 3 centriole elongation regulator
Host:
Rabbit
Immunogen:
Recombinant Human C2 domain-containing protein 3 protein (2079-2265AA)
Isotype:
IgG
Protein Details:
C2 domain-containing protein 3
Purity:
>95%
Purification:
Protein G Purified
Shipping Conditions:
Blue Ice
Storage Conditions:
-20Â[o]C or -80Â[o]C
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody