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Antibodies

TTI1 Antibody

Product Sizes
50ug
£305.00
OACA09792-50UG
100ug
£463.00
OACA09792-100UG
About this Product
SKU:
OACA09792
Additional Names:
KIAA0406;Protein SMG10;smg-10;smg-10 homolog; nonsense mediated mRNA decay factor;Tel two interacting protein 1;TEL2-interacting protein 1 homolog;TELO2-interacting protein 1 homolog.
Clonality:
Polyclonal
Conjugate:
Unconjugated
Extra Details:
Regulator of the DNA damage response (DDR). Part of the TTT complex that is required to stabilize protein levels of the phosphatidylinositol 3-kinase-related protein kinase (PIKK) family proteins. The TTT complex is involved in the cellular resistance to DNA damage stresses; like ionizing radiation (IR); ultraviolet (UV) and mitomycin C (MMC). Together with the TTT complex and HSP90 may participate in the proper folding of newly synthesized PIKKs. Promotes assembly; stabilizes and maintains the activity of mTORC1 and mTORC2 complexes; which regulate cell growth and survival in response to nutrient and hormonal signals.
Gene Details:
TELO2 interacting protein 1
Host:
Rabbit
Immunogen:
Recombinant Human TELO2-interacting protein 1 homolog protein (692-858AA)
Isotype:
IgG
Protein Details:
TELO2-interacting protein 1 homolog
Purity:
>95%
Purification:
Protein G Purified
Shipping Conditions:
Blue Ice
Storage Conditions:
-20Â[o]C or -80Â[o]C
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody